diff --git a/Lib/wsgiref/handlers.py b/Lib/wsgiref/handlers.py
index fcb8e239373..a5f7109c266 100644
--- a/Lib/wsgiref/handlers.py
+++ b/Lib/wsgiref/handlers.py
@@ -434,6 +434,10 @@ class CGIHandler(BaseCGIHandler):
     """
 
     wsgi_run_once = True
+    # Do not allow os.environ to leak between requests in Google App Engine
+    # and other multi-run CGI use cases.  This is not easily testable.
+    # See http://bugs.python.org/issue7250
+    os_environ = {}
 
     def __init__(self):
         BaseCGIHandler.__init__(
diff --git a/Misc/NEWS b/Misc/NEWS
index 9729699d229..0564d138d4c 100644
--- a/Misc/NEWS
+++ b/Misc/NEWS
@@ -35,6 +35,9 @@ Core and Builtins
 Library
 -------
 
+- Issue #7250: Fix info leak of os.environ across multi-run uses of
+  wsgiref.handlers.CGIHandler.
+
 - Issue #1729305: Fix doctest to handle encode error with "backslashreplace".
 
 - Issue #691291: codecs.open() should not convert end of lines on reading and