diff --git a/Misc/NEWS b/Misc/NEWS
index 296d8643509..874498b99fa 100644
--- a/Misc/NEWS
+++ b/Misc/NEWS
@@ -771,6 +771,9 @@ Library
 Build
 -----
 
+- Do not accidentally include the directory containing sqlite.h twice when
+  building sqlite3.
+
 - Issue #11217: For 64-bit/32-bit Mac OS X universal framework builds,
   ensure "make install" creates symlinks in --prefix bin for the "-32"
   files in the framework bin directory like the installer does.
diff --git a/setup.py b/setup.py
index 896d6046f03..39751c3b0ae 100644
--- a/setup.py
+++ b/setup.py
@@ -1045,10 +1045,15 @@ class db_found(Exception): pass
             else:
                 sqlite_extra_link_args = ()
 
+            include_dirs = ["Modules/_sqlite"]
+            # Only include the directory where sqlite was found if it does
+            # not already exist in set include directories, otherwise you
+            # can end up with a bad search path order.
+            if sqlite_incdir not in self.compiler.include_dirs:
+                include_dirs.append(sqlite_incdir)
             exts.append(Extension('_sqlite3', sqlite_srcs,
                                   define_macros=sqlite_defines,
-                                  include_dirs=["Modules/_sqlite",
-                                                sqlite_incdir],
+                                  include_dirs=include_dirs,
                                   library_dirs=sqlite_libdir,
                                   runtime_library_dirs=sqlite_libdir,
                                   extra_link_args=sqlite_extra_link_args,