diff --git a/Makefile.pre.in b/Makefile.pre.in
index ee1b0ddbfec..a35811c0576 100644
--- a/Makefile.pre.in
+++ b/Makefile.pre.in
@@ -1148,7 +1148,7 @@ TAGS::
 	for i in $(SRCDIRS); do etags -a $$i/*.[ch]; done
 
 # Sanitation targets -- clean leaves libraries, executables and tags
-# files, which clobber removes those as well
+# files, which clobber removes as well
 pycremoval:
 	find $(srcdir) -name '*.py[co]' -exec rm -f {} ';'
 
@@ -1168,6 +1168,7 @@ clean: pycremoval
 	find . -name '*.s[ol]' -exec rm -f {} ';'
 	find build -name 'fficonfig.h' -exec rm -f {} ';' || true
 	find build -name 'fficonfig.py' -exec rm -f {} ';' || true
+	-rm -f Lib/lib2to3/*Grammar*.pickle
 
 profile-removal:
 	find . -name '*.gc??' -exec rm -f {} ';'