diff --git a/src/cmd/compile/internal/ssa/gen/AMD64Ops.go b/src/cmd/compile/internal/ssa/gen/AMD64Ops.go
index a3b29049df6..e6d66957ddd 100644
--- a/src/cmd/compile/internal/ssa/gen/AMD64Ops.go
+++ b/src/cmd/compile/internal/ssa/gen/AMD64Ops.go
@@ -748,6 +748,7 @@ func init() {
 				clobbers: buildReg("DI"),
 			},
 			faultOnNilArg0: true,
+			unsafePoint:    true, // FP maintenance around DUFFCOPY can be clobbered by interrupts
 		},
 		{name: "MOVOconst", reg: regInfo{nil, 0, []regMask{fp}}, typ: "Int128", aux: "Int128", rematerializeable: true},
 
@@ -786,6 +787,7 @@ func init() {
 			clobberFlags:   true,
 			faultOnNilArg0: true,
 			faultOnNilArg1: true,
+			unsafePoint:    true, // FP maintenance around DUFFCOPY can be clobbered by interrupts
 		},
 
 		// arg0 = destination pointer
diff --git a/src/cmd/compile/internal/ssa/gen/ARM64Ops.go b/src/cmd/compile/internal/ssa/gen/ARM64Ops.go
index b402e35ea6f..2424e67e201 100644
--- a/src/cmd/compile/internal/ssa/gen/ARM64Ops.go
+++ b/src/cmd/compile/internal/ssa/gen/ARM64Ops.go
@@ -507,6 +507,7 @@ func init() {
 				clobbers: buildReg("R20 R30"),
 			},
 			faultOnNilArg0: true,
+			unsafePoint:    true, // FP maintenance around DUFFZERO can be clobbered by interrupts
 		},
 
 		// large zeroing
@@ -547,6 +548,7 @@ func init() {
 			},
 			faultOnNilArg0: true,
 			faultOnNilArg1: true,
+			unsafePoint:    true, // FP maintenance around DUFFCOPY can be clobbered by interrupts
 		},
 
 		// large move
diff --git a/src/cmd/compile/internal/ssa/opGen.go b/src/cmd/compile/internal/ssa/opGen.go
index 9efa1bfcc4b..408c855dbdd 100644
--- a/src/cmd/compile/internal/ssa/opGen.go
+++ b/src/cmd/compile/internal/ssa/opGen.go
@@ -13119,6 +13119,7 @@ var opcodeTable = [...]opInfo{
 		auxType:        auxInt64,
 		argLen:         3,
 		faultOnNilArg0: true,
+		unsafePoint:    true,
 		reg: regInfo{
 			inputs: []inputInfo{
 				{0, 128},   // DI
@@ -13196,6 +13197,7 @@ var opcodeTable = [...]opInfo{
 		clobberFlags:   true,
 		faultOnNilArg0: true,
 		faultOnNilArg1: true,
+		unsafePoint:    true,
 		reg: regInfo{
 			inputs: []inputInfo{
 				{0, 128}, // DI
@@ -20734,6 +20736,7 @@ var opcodeTable = [...]opInfo{
 		auxType:        auxInt64,
 		argLen:         2,
 		faultOnNilArg0: true,
+		unsafePoint:    true,
 		reg: regInfo{
 			inputs: []inputInfo{
 				{0, 1048576}, // R20
@@ -20760,6 +20763,7 @@ var opcodeTable = [...]opInfo{
 		argLen:         3,
 		faultOnNilArg0: true,
 		faultOnNilArg1: true,
+		unsafePoint:    true,
 		reg: regInfo{
 			inputs: []inputInfo{
 				{0, 2097152}, // R21